Phytosphingosine

Phytosphingosine is a natural, skin-identical active ingredient for Personal Care products

Naturally present in the skin
Effectively reduces the signs of acne
Inhibits the growth of micro-organisms on the skin
Reduces redness and inflamed skin
Active at very low concentrations.

Properties

During the last decade, an increasing number of scientific articles report the importance of the biological role of breakdown products of Stratum Corneum lipids. Free sphingoid bases, such as Phytosphingosine are a recent addition to this family of active lipids, which emerged from studies of breakdown products from Ceramides. Free sphingoid bases are naturally found in the human body, and are present at high levels in the Stratum Corneum. Most of the published research on free sphingoid bases deals with the inhibition of micro organisms and their "second messenger" function. Because of these properties, free phingoid bases are considered to be part of the skin's natural defence system. Recently performed in-vitro and in-vivo studies show that Phytosphingosine has anti-microbial properties against Propionibacterium acnes and Staphylococcus aureus for example. Furthermore, additional studies confirm the biological role Phytosphingosine has as a natural anti-inflammatory agent. Consequently, free sphingoid bases seem to have a wide range of product applications, especially those addressing microbial imbalances with associated inflammation, such as Acne. In addition to the in-vitro and in-vivo studies, clinical studies have been performed on acne patients by a group of dermatologists in France, which demonstrates the potential of Phytosphingosine to enhance or complement existing acne therapies.

Recommended usage concentration